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This paper is in the following e-collection/theme issue:

Reviews in AI (160) Digital Mental Health Interventions, e-Mental Health and Cyberpsychology (3079) Innovations in Mental Health Systems (656) Generative Language Models Including ChatGPT (1419) AI Language Models in Health Care (696)

Published on in Vol 5 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/80348, first published .
Doctor's gloved hand touches futuristic medical interface displaying brain scans and heart monitor.

Large Language Model–Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards

Large Language Model–Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards

Authors of this article:

Ha Na Cho1 Author Orcid Image ;   Jiayuan Wang1 Author Orcid Image ;   Di Hu1 Author Orcid Image ;   Kai Zheng1 Author Orcid Image
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Journals

  1. Moya-Sanchez D. Artificial Intelligence in Psychiatry: A Clinical Framework for the Supervised Integration of Large Language Models when Patients Are Already Using Them. AI in Neuroscience 2026 View