AI-Driven Digital Twin Architecture for Multimodal Prediction and Adaptive Intervention in Cognitive Aging

Yu Liu   ^{1 *} , MD, MS ;   Keming Yan   ^{1 *} , MS ;   Siying Ma   ² , MS ;   Hao Deng   ³ , MD, MPH, MBA, DrPH ;   Jian Kong   ¹ , MD, MPH, MS

¹ Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, United States

² Microsoft Customer and Partner Solutions (MCAPS), Microsoft, Cambridge, MA, United States

³ Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, United States

*these authors contributed equally