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Published on in Vol 5 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/95081, first published .
Tumor Board meeting with LLM prompt on laptop screen.

Augmenting Head and Neck Multidisciplinary Tumor Board Recommendations With Locally Run Large Language Models: Prospective Evaluation of Real-World Implementation

Augmenting Head and Neck Multidisciplinary Tumor Board Recommendations With Locally Run Large Language Models: Prospective Evaluation of Real-World Implementation

Christoph Raphael Buhr   1, 2 , MBA, MD, Dr ;   Lukas Müller   3 , MBA, MD, Dr, PhD ;   Daniel Pinto dos Santos   3 , MD, PD Dr ;   Daniel Thiem   4 , MHBA, MD, PD Dr Dr ;   Jean-Jacques Ponciano   1, 4 , MSc, Dr ;   Maximilian Krüger   4 , MD, PD Dr Dr ;   Karoline O'Brien   1 , MD, Dr ;   Justus Kaufmann   5 , MD, Dr ;   Hildegard Nolte   6 , MD, Dr ;   Martin Gartenschläeger   3 , MD, Dr ;   Stefanie Zimmer   7 , MD, Dr ;   Sebastian Altmann   8 , MD, PD Dr ;   Andrew Blaikie   2 , BSC, MBchB, FRCOphth, PhD, MD ;   Christian Ruckes   9 , PhD ;   Christoph Matthias   1 , MD, Prof Dr ;   Sebastian Kuhn   10 , MME, MD, Prof Dr ;   Jonas Eckrich   1 , MD, Dr

1 Department of Otorhinolaryngology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

2 University of St Andrews, School of Medicine, St Andrews, United Kingdom

3 Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

4 Department of Oral and Maxillofacial Surgery-Plastic Surgery, University Medical Center Mainz of the Johannes Gutenberg-University Mainz, Mainz, Germany

5 Department of Radiotherapy and Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

6 Department of Hematology & Medical Oncology, University Medical Center Mainz of the Johannes Gutenberg-University Mainz, Mainz, Germany

7 Institute of Pathology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

8 Department Neuroradiology, University Medical Center Mainz of the Johannes Gutenberg-University Mainz, Mainz, Germany

9 Interdisciplinary Center for Clinical Trials (IZKS), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

10 Institute for Digital Medicine Philipps-University Marburg and University Hospital of Giessen and Marburg, Marburg, Marburg, Germany

Corresponding Author:

  • Christoph Raphael Buhr, MBA, MD, Dr
  • Department of Otorhinolaryngology
  • University Medical Center of the Johannes Gutenberg-University Mainz
  • Langenbeckstraße 1
  • Mainz
  • Germany
  • Phone: 49 6131 17 7362
  • Email: buhrchri@uni-mainz.de