Responsible Health AI

Performance of Large Language Models in Diagnosing Rare Hematologic Diseases and the Impact of Their Diagnostic Outputs on Physicians: Combined Retrospective and Prospective Study

Hongbin Yu, Tian Chen, Xin Zhang, Yunfan Yang, Qinyu Liu, Chenlu Yang, Kai Shen, He Li, Wenjiao Tang, Xushu Zhong, Xiao Shuai, Xinmei Yu, Yi Liao, Chiyi Wang, Huanling Zhu, Yu Wu

J Med Internet Res 2025 (Oct 09); 27:e77334

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Principles and Practices of Community Engagement in AI for Population Health: Formative Qualitative Study of the AI for Diabetes Prediction and Prevention Project

Ibukun-Oluwa Omolade Abejirinde, Ijeoma Uchenna Itanyi, Kathy Kornas, Remziye Zaim, Shion Guha, Victoria Chui, Lorraine Lipscombe, Laura C Rosella, James Shaw

J Particip Med 2025 (Oct 02); 17:e69497

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Large Language Models in Lung Cancer: Systematic Review

Ruikang Zhong, Siyi Chen, Zexing Li, Tangke Gao, Yisha Su, Wenzheng Zhang, Dianna Liu, Lei Gao, Kaiwen Hu

J Med Internet Res 2025 (Sep 30); 27:e74177

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Patient Participation in AI for Health Curriculum

Kirsten Ostherr, Waverly Huang, Ana Park, Tom Punnen, Bhavik Tadigotla, Valencia Robinson, Andrea Downing

J Particip Med 2025 (Sep 24); 17:e69942

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Extension of the Consolidated Criteria for Reporting Qualitative Research Guideline to Large Language Models (COREQ+LLM): Protocol for a Multiphase Study

Leonard Fehring, Julian Frings, Paul Rust, Christian Kempny, Petra A Thürmann, Sven Meister

JMIR Res Protoc 2025 (Sep 24); 14:e78682

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Machine Learning in Health Economic Evaluations: Protocol for a Scoping Review

Hanan Daghash, Ashleigh Kernohan, Rosiered Brownson-Smith, Rohan Pandey, Ananya Ananthakrishnan, Cen Cong, Victoria Riccalton, Edward Meinert, Gurdeep S Sagoo

JMIR Res Protoc 2025 (Sep 24); 14:e77494

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Disease Activity Assessment Frequency in Rheumatoid Arthritis: A Retrospective Observational Study of the Medical Support System for Rheumatoid Arthritis System Implementation

Mari Yamamoto, Yuki Kataoka, Yasushi Tsujimoto, Fumika Nagase, Keita Iwasaki, Yuuki Ito, Hiroki Ikai, Tsuyoshi Watanabe, Waka Yokoyama-Kokuryo, Naoho Takizawa, Yoshiro Fujita

JMIR Form Res 2025 (Sep 23); 9:e74222

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Comparative Diagnostic Performance of a Multimodal Large Language Model Versus a Dedicated Electrocardiogram AI in Detecting Myocardial Infarction From Electrocardiogram Images: Comparative Study

Haemin Lee, Sooyoung Yoo, Joonghee Kim, Youngjin Cho, Dongbum Suh, Keehyuck Lee

JMIR AI 2025 (Sep 17); 4:e75910

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The Right to Explanation in AI: In a Lonely Place

Alycia Noë, Sarah Bouhouita-Guermech, Ma'n H Zawati

J Med Internet Res 2025 (Sep 12); 27:e64482

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Toward Human-Centered Artificial Intelligence for Users’ Digital Well-Being: Systematic Review, Synthesis, and Future Directions

Youngsoo Shin

JMIR Hum Factors 2025 (Sep 10); 12:e69533

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Applications of Federated Large Language Model for Adverse Drug Reactions Prediction: Scoping Review

David Guo, Kim-Kwang Raymond Choo

J Med Internet Res 2025 (Sep 08); 27:e68291

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Medical Expert Knowledge Meets AI to Enhance Symptom Checker Performance for Rare Disease Identification in Fabry Disease: Mixed Methods Study

Anne Pankow, Nico Meißner-Bendzko, Jessica Kaufeld, Laura Fouquette, Fabienne Cotte, Stephen Gilbert, Ewelina Türk, Anibh Das, Christoph Terkamp, Gerhard-Rüdiger Burmester, Annette Doris Wagner

JMIR AI 2025 (Aug 28); 4:e55001

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Evaluating the Quality and Understandability of Radiology Report Summaries Generated by ChatGPT: Survey Study

Alexis Sunshine, Grace H Honce, Andrew L Callen, David A Zander, Jody L Tanabe, Samantha L Pisani Petrucci, Chen-Tan Lin, Justin M Honce

JMIR Form Res 2025 (Aug 27); 9:e76097

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Exploring the Characteristics of Online Counseling Chat Services for Youth in Europe: Web Search Study

Irati Higuera-Lozano, Virvatuli Uusimäki, Tuuli Pitkänen, Elke Denayer, Alexis Dewaele, Katalin Felvinczi, Lien Goossens, Zsuzsa Kaló, Mónika Rényi, María Cabello

JMIR Ment Health 2025 (Aug 20); 12:e67949

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Exploring the Application of AI and Extended Reality Technologies in Metaverse-Driven Mental Health Solutions: Scoping Review

Aliya Tabassum, Ibrahim Ghaznavi, Alaa Abd-Alrazaq, Junaid Qadir

J Med Internet Res 2025 (Aug 19); 27:e72400

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Understanding the Impact of AI Doctors’ Information Quality on Patients’ Intentions to Adopt AI for Independent Diagnosis: Scenario-Based Experimental Study

Yongmei Liu, Zichun Wang, Bo Peng

J Med Internet Res 2025 (Aug 19); 27:e62885

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The Ability of AI Therapy Bots to Set Limits With Distressed Adolescents: Simulation-Based Comparison Study

Andrew Clark

JMIR Ment Health 2025 (Aug 18); 12:e78414

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Placebo, Nocebo, and Machine Learning: How Generative AI Could Shape Patient Perception in Mental Health Care

Charlotte Blease

JMIR Ment Health 2025 (Aug 15); 12:e78663

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Recapitulation of Ageism in Artificial Intelligence–Generated Images: Longitudinal Comparative Study

Lindsey Martens, Nicole Virgin, Phillip Hoffarth, Jade Goodwill, Nicole Derenne, Richard Van Eck, Marilyn Klug, Gunjan Dhawan Manocha, Donald Jurivich

J Med Internet Res 2025 (Aug 13); 27:e68428

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Artificial Intelligence (AI) and Emergency Medicine: Balancing Opportunities and Challenges

Félix Amiot, Benoit Potier

JMIR Med Inform 2025 (Aug 13); 13:e70903

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