Treatment Recommendations for Clinical Deterioration on the Wards: Development and Validation of Machine Learning Models

Eric Pulick   ¹ , MS ;   Kyle A Carey   ² , MPH ;   Tonela Qyli   ³ , MD ;   Madeline K Oguss   ³ , MS ;   Jamila K Picart   ⁴ , MD ;   Leena Penumalee   ⁵ , MD ;   Lily K Nezirova   ⁶ , MD ;   Sean T Tully   ⁶ , DO ;   Emily R Gilbert   ⁶ , MD ;   Nirav S Shah   ⁷ , MD, MPH ;   Urmila Ravichandran   ⁸ , MS ;   Majid Afshar   ^{3, 9} , MD, MSCR ;   Dana P Edelson   ² , MD, MS ;   Yonatan Mintz   ¹ , PhD ;   Matthew M Churpek   ^{3, 9} , MD, MPH, PhD

¹ Department of Industrial and Systems Engineering, University of Wisconsin-Madison, Madison, WI, United States

² Department of Medicine, University of Chicago, Chicago, IL, United States

³ Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States

⁴ Department of Surgery, University of Michigan, Ann Arbor, MI, United States

⁵ Department of Medicine, Northwestern Memorial Hospital, Chicago, IL, United States

⁶ Department of Medicine, Loyola University Medical Center, Chicago, IL, United States

⁷ Department of Medicine, Endeavor Health, Evanston, IL, United States

⁸ Department of Data Analytics, Endeavor Health, Evanston, IL, United States

⁹ Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United States